Little Known Facts About ceesdekker.

Little Known Facts About ceesdekker.

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Utilizing single-molecule optical and AFM imaging and drive-spectroscopy approaches, we find to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our analysis interests include:

It was only inside the nineteen nineties even though, when nanotechnology experienced Sophisticated to the degree where by single molecules may very well be manipulated, that the very first experimental products commenced to appear.

[Laughs] ‘It was definitely an excellent risk! At time, I was well knowledgeable that it could go Completely wrong Which I could grow to be much less effective, but I just ignored that. Curiosity has normally been my strongest driving pressure. And by chance it all worked out.’

2007, 1st serious-time detection of strand exchange in homologous recombination by RecA; discovery of the small persistence length of ends of microtubules; and fixed the system of biosensing with carbon nanotubes

2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initially ever research on the dynamics DNA supercoils and the invention of supercoil hopping

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes

All parameters have been a similar for every panel in this video, except for the Preliminary placement in the 6hb rod (demonstrated in blue) to the nanopore. Simulations that terminated early as a consequence of translocation from the rod with the pore are marked by a grey track record.

Dynamic ParB–DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation

‘Yes, I recognize people had been amazed at the time. At the end of the nineties, After i was in my forties, I used to be Professor of Molecular Electronics and I've to confess that it had become a little bit bored, I didn’t master Significantly anymore. The sphere went a lot more into the appliance facet, how you can combine nanotubes into Digital circuits.

There was one particular challenge while — we didn't notice any measurable electrical conduction from The only polymer molecules. We concluded that at The one-molecule stage, conducting polymers ended up basically not these types of great conductors, which was rather disappointing. We Therefore broadened our see to try to locate much more ceesdekker promising molecules.

FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division

Afterwards we spoke yet again briefly for the reason that Dekker felt that our dialogue of his religion immediately became purely philosophical, whereas Additionally, it concretely aids him in his operate.

Visualization of unstained DNA nanostructures with advanced in-concentrate transmission electron microscopy approaches

The biophysicist from Delft – who has long been Among the most cited researchers within the Netherlands For many years – takes his obligation to lead towards the rationalization and popularisation of his get the job done with the border of physics and biology incredibly critically and frequently seems while in the media; if not to look at his perform, then about the relationship involving science and his Christian faith.